Vaccine after-effects

About 50 million Indians, 3.5% of the population, had taken the first shot of their COVID-19 vaccine before I joined the queue on Monday after lunch. It went very fast. I had the jab less than an hour after I joined the queue. A half hour under observation at the hospital after that, and I was out. During the wait I downloaded my certificate of vaccination. Pretty smooth systems, I thought. The Family had got her first shot the previous week. We’d decided not to take the shots together because both of us might have had to deal with the usual after-effects of a vaccination. She hadn’t had any effects, not even a soreness at the site of the injection.

Sometimes I wonder whether all this happened because I didn’t forward that WhatsApp message to ten people. – forwarded on WhatsApp

Four hours later I noticed the first twinges from my immune system. I developed a slightly runny nose. This was a probably my non-specific immune system responding. Four hours later, my internal defense system realized that there was a persistent invader which needed more drastic measures. I developed a very high fever, bad enough to set my teeth chattering. A fever is one of the defense mechanisms that the body has against invading pathogens. Raising the body temperature stresses cells. An out of control fever can be killing, but it is a scorched-earth measure that an immune system adopts to slow an invader before new forces are brought into action.

By end of March the fraction vaccinated had risen to about 3.5 in every 100 people.

I was fairly certain that the fever would recede fast. I had a restless night, but by morning the fever was gone. I had the usual post-fever distress, a mild headache, a touch of nausea for the rest of the day. A mild fever recurred in the afternoon. I dealt with it as I have done whenever I had a bad infection: sleep. This time round I knew that the symptoms would be gone in a day as the adaptive immune system comes into play. This prediction was right. I woke in the morning at my usual time, still with sniffles, but otherwise fresh. There was a mild soreness at the spot of the injection, but I expect it to fade.

Sputnik V emergency use | India to discuss approval of Russian vaccine – MoneyControl news Report

My reaction to the vaccine were pretty much average. About six of the ten males in my age group I talked to had similar after-effects to the Astra-Zeneca vaccine, fading about a day and a half after the shot. One, an older and somewhat immuno-compromised person, had fever and body ache that lasted longer. Three had no after effects. The Family had talked a more eclectic set of women, and it turned out that among women of all ages about half suffered the same reactions as me. If you have this kind of a reaction you can be pretty certain that your immune system is reacting as it is expected to.

At most, perhaps 5% of people have been infected (with SARS-CoV-2)….If all that pain, suffering and economic destruction got us to 5%, what will it take to get us to 60%? That’s a sobering thought. All of that suffering and death is just getting started.” Michael Oseterholm in The Guardian, Jun 10, 2020

We will go on another small trip at the end of next week. Unfortunately, the second wave is still raging across the country, so we will have to remain masked and vigilant during the trip. After all this first shot has only primed the immune system, and the second shot is yet to come. The usual precautions are still needed.

There are just three simple things to remember about COVID-19: mask up, keep your distance when possible, and do not gather with many others.